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A1CR
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Joined: 18 Jan 2006
Posts: 559
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 Posted: Fri Feb 17, 2006 3:57 am Post subject: CR in Primates Preserves Melatonin With Age |
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[posted on behalf of MR; 2001-07-15]
J Clin Endocrinol Metab 2001 Jul;86(7):3292-5
Dietary caloric restriction prevents the age-related decline in plasma melatonin levels of rhesus monkeys.
Roth GS, Lesnikov V, Lesnikov M, Ingram DK, Lane MA.
Rhesus monkeys exhibit an age-associated decrease in peak plasma melatonin levels analogous to that reported for humans.
This decrease is essentially abolished in monkeys subjected to a 30% reduction in caloric intake over a 12-yr period. The caloric restriction (CR) effect does not seem to be a reversal, but rather a long-term prevention, of the age-related decline in hormone concentrations. ....
PMID: 11443203
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