cron-web.org

[MR]

[posted on behalf of CRON4healthy future; 17 Mar 2003]

Johns Hopkins is chiming on this one.

The punchline is that there are 117 monkeys, and 8(!) were DR, and 109 ate
their brains out.

The AL monkeys had a 2.6 fold increased risk of death. Hyperinsulinemia
led to a 3.7 fold increase in death, with the risk of death decreasing 7%
per unit of insulin sensitivity. In other words, less insulin sensitivity
means less life.

DR monkeys lived 32 years on average, AL lived 25 years. Interestingly,
the longest lived monkey was a diabetic monkey who lived to 40 years old
despite being ab-libitum. I guess luck will play a factor in all of this
as well.

This may have been posted before, but I guess this time we have the PMID as
well.

J Gerontol A Biol Sci Med Sci 2003 Mar;58(3):B212-9

Mortality and Morbidity in Laboratory-maintained Rhesus Monkeys and Effects
of Long-term Dietary Restriction.

Bodkin NL, Alexander TM, Ortmeyer HK, Johnson E, Hansen BC.

Obesity and Diabetes Research Center, Department of Physiology, School of
Medicine, University of Maryland, Baltimore. Department of Biostatistics,
Johns Hopkins University, Baltimore, Maryland.