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For Fruit Flies: Calories May Not Count in Life Extension

 
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PostPosted: Wed Jan 18, 2006 7:33 am    Post subject: For Fruit Flies: Calories May Not Count in Life Extension Reply with quote



From:

http://www.sciencenews.org/articles/20050611/food.asp

Quote:
An overwhelming amount of new data has built up over the past several decades suggesting that limiting food intake can extend almost any organism's life, from the lowly flatworm to the ubiquitous lab mouse. Although scientists haven't yet nailed down the mechanism behind this phenomenon, most hypotheses have focused on the number of calories in a diet—the fewer an organism takes in while still meeting its nutritional needs, the longer it's likely to live (SN: 5/11/02, p. 291: http://www.sciencenews.org/articles/20020511/fob2.asp).


...but...

Quote:
Partridge's team made a surprising finding. Although flies eating the new diets took in about as much food as a group eating regular chow did, those on the reduced-protein diet lived about 24 days longer than the average fruit fly's life span of 40 days. That extension, of about 60 percent, rivals the added life span of flies on a typical caloric-restriction diet.


...and:


Quote:
"This is a very fascinating hypothesis that we have to explore more deeply," says Luigi Fontana, a clinical investigator at Washington University in St. Louis and at the Italian National Institute of Health in Rome. He notes that if the same concept works in people, the currently popular "low carb" diets, in which people eat large amounts of protein but fewer sugars, could be undermining the dieters' longevity. "It's certainly a possibility," he says.


Well, Partridge's team focused on flies -- not mammals. Rats on "high"-protein CR diets live longer/healthier than rats on lower-protein regimens.
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