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[A1CR]

Are we required to modify our protein intake if we CR and
become infected?
The paper below suggests the reply to the question is
"Probably." A decision whether the nature of our CR
requires specially
consideration appears to be whether we have
http://en.wikipedia.org/wiki/Edematous symptoms that result
from our CR, as
indicated by swelling of the feet and lower legs.

Kurpad AV.
The requirements of protein & amino acid during acute &
chronic infections.
Indian J Med Res. 2006 Aug;124(2):129-48.
PMID: 17015927


Nutrition and infection interact with each other in a
synergistic
vicious cycle, leading to an adverse nutritional status and
increased
susceptibility to infection. Infectious episodes result in
hypermetabolism
and a negative nitrogen balance which is modulated by
hormones, cytokines
and other pro-inflammatory mediators, and is compounded by a
reduced food
intake. The extent of the negative nitrogen balance varies
with the type of
infection and its duration; however, it is reasonable to
suggest that the
loss of body protein could be minimized by the provision of
dietary
nitrogen, although anorexia will limit this. Further,
distinctions need to
be made about the provision of nutrients or protein during
the catabolic and
anabolic or recovery phase of the infection, since the
capacity of the body
to retain protein is enhanced in the anabolic recovery
phase. Meeting the
increased requirement for protein (and other nutrients) in
infection does
not imply a complete therapeutic strategy. Infections need
to be treated
appropriately, with nutrition as an adjunct to the
treatment. Prior
undernutrition could also impair the body's response to
infection, although
the weight of the evidence would suggest that this happens
more particularly
in oedematous undernutrition. In general, the amount of
extra protein that
would appear to be needed is of the order of 20-25 per cent
of the
recommended intake, for most infections. In acute
infections, this is
particularly relevant during the convalescence period.
Community trials have
suggested that lysine supplementation to the level required
for normal daily
nutriture, in predominantly wheat eating or potentially
lysine deficient
communities, improves immune function among other functional
nutritional
parameters; however, there is as yet insufficient evidence
to suggest a
specific requirement for amino acids in infections over and
above the normal
daily requirement as based on recent evidence. Some clinical
studies that
have showed benefits with specific amino acids through
selected clinical
outcomes ...