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Calorie Restriction with Optimum Nutrition Forum
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 Posted: Mon Feb 27, 2006 12:16 am Post subject: Why Exercise probably doesn't work |
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I thought this recent study in the March 2006 issue of Metabolism was particularly insightful into reasons why exercise may not work "as well" as interventions like caloric restriction.
In this study, the investigators tried to "titrate" the amount of exercise to the amount of food the person was eating, and have them "follow each other" as they walked the amount of food up to an "overfeeding" amount. In other words, if you eat more, can you just exercise it away?
Well, not entirely. They showed that fasting insulin levels did not lower to "baseline" when you exercise an amount that would be expected to "remove" the extra energy. In fact, they were a little bit higher than the group that just ate more.....
But, the "area under the curve" for insulin after a meal was reduced considerably by the exercise.
All in all, the fasting insulin result may indicate that they did not titrate things as well as they thought, but, I think in general it indicates that attempting to titrate exercise to the standard American diet is only a "half solution" to the problem. The reason this is so may have to do more with the fact that it is too hard to actually calculate and implement what would be most beneficial, but, there is a distinct possibility that exercise is simply incapable of producing the necessary endocrinological milieu for maximal lifespan extension.
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http://www.journals.elsevierhealth.com/periodicals/ymeta/article/PIIS0026049505003732/abstract
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"A state of relative insulin insensitivity was then induced by systematic overfeeding (OF) to generate a daily energy surplus of 768 ± 203 kcal/d for 3 days, and the oral glucose tolerance test was repeated. In the following 24 hours, the OF was increased ∼2-fold (+6284 ± 1669 kJ/d) and subjects performed a single bout of exercise (expenditure = 3063 ± 803 kJ) to maintain the same energy surplus (+3125 ± 933 kJ/d; OF and exercise) as OF."
"A single exercise bout, opposed by a concurrent energy surplus, decreased the insulin response to a glucose challenge, but only partially restored the insulin AUC to baseline and had no impact on C-ISI or fasting insulin concentrations." - Metabolism |
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