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cron-web.org Calorie Restriction with Optimum Nutrition Forum
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A1CR Site Admin
Joined: 18 Jan 2006 Posts: 559
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Posted: Fri Aug 11, 2006 9:30 am Post subject: CR monkey energy use |
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It seems that there were no significant differences in the
energy expended
in the rhesus monkey CR experiments.
Raman A, Ramsey JJ, Kemnitz JW, Baum ST, Newton W, Colman
RJ, Weindruch R,
Beasley MT, Schoeller DA.
Influences of calorie restriction and age on energy
expenditure in the
rhesus monkeys.
Am J Physiol Endocrinol Metab. 2006 Aug 8
PMID: 16896169 http://tinyurl.com/nsc5p
Caloric restriction (CR) ... a marker of aging is
decreased energy
expenditure (EE). ... (Macaca mulata), data from 41 males
(M) and 26 females
(F) subjected to 9 or 15 years of CR ... 11-28 years of age
... Total 24hEE
was divided into day (day EE), night (night EE) and day
minus night [(D-N)
EE]. M CR monkeys showed a lower 24hEE (mean±sd=568+/-96
kcal/d; p<0.0001)
than controls (C) (630±129 kcal/d). CR M had a lower night
EE (diff.=36 kcal
p<0.0001) compared to C M, but after adjusting for FFM and
FM, night EE was
not different between CR and C M (p=0.72). The 24hEE
decreased with age (13
kcal decrease/yr; p<0.0001), but there was no difference
between CR and C.
Adjusted for FFM and FM, (D-N) EE decreased with age (9
kcal/year; p<0.0001)
with no interaction with age (p=0.72). ... age-matched ... F
had a lower
24hrEE (496±84 kcal/d) than M (636±139 kcal/d) (p<0.0001).
Adjusting for FFM
and FM, night EE was lower in the F compared to M (diff.=18
kcal; p=0.077).
Night EE did not differ between CR and C younger monkeys
after adjusting for
FFM and FM. In conclusion, CR did not alter the age-related
decrease in EE
with CR. |
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