cron-web.org

[Matthewlake]

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[Matthewlake]

Elevated inflammation involved in anxiety disorders

BACKGROUND: Anxiety is a complex feeling of uneasiness, fear and worry, which has been associated with pulmonary, cardiovascular and other adverse health conditions. The aim of this work is to examine the association of the anxious state with inflammation and coagulation factors, in persons free of cardiovascular disease. METHODS: From May 2001 to December 2002 we randomly enrolled 453 men (19 to 89 years old) and 400 women (18 to 84 years old) stratified by age and gender, from Attica area, Greece. Among others, various inflammation and coagulation markers (C-reactive protein (CRP), amyloid-A, interleukin-6, tumor necrosis factor-alpha, white blood cell (WBC), homocysteine and fibrinogen) were evaluated in relation to the anxious state (assessed by the Spielberger State Anxiety Inventory, STAI) of participants, after several adjustments made for potential confounders. RESULTS: STAI score was positively correlated with C-reactive protein (rho = 0.18, p = 0.01), tumor necrosis factor-alpha (rho = 0.11, p = 0.03), interleukin-6 (rho = 0.09, p=0.03), homocysteine (rho = 0.10, p = 0.03) and fibrinogen levels (rho = 0.08, p = 0.04), in men, and positively correlated with C-reactive protein (rho = 0.22, p = 0.01), white blood cell counts (rho = 0.15, p = 0.02), interleukin-6 (rho = 0.12, p = 0.02), homocysteine (rho = 0.07, p = 0.04) and fibrinogen levels (rho = 0.07, p = 0.04), in women. These associations remained significant even after various adjustments were made. CONCLUSION: This study revealed that anxiety was associated with inflammation and coagulation markers in cardiovascular disease-free people. This may raise a hypothesis of a pathway leading to increased cardiovascular events in anxious individuals.

PMID: 16005881 [PubMed - in process]

[Matthewlake]

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[Matthewlake]

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[Matthewlake]

Power Yoga

Just recieved some stuff from amazon today, a new steamer, much better than the crappy old one I had... and a yoga dvd called "Power Yoga" with Rodney yee. So I'll be doing the whole workout about 3 times a week or more, depends on how I feel. But with do some yoga everyday. I'm feeling quite good now, still no palpitations, no adrenaline rushes, can recover from a bit of stress better. Just have to get this sinus trouble sorted now. My doctor says its an allergy when I seen him last, even though I've had allergies in the past and the symptoms were quite different.

I did do some yoga poses and found that it does help clear my nose somewhat...

[Matthewlake]

Started YOGA today!

It was excellent, made me feel relaxed after doing the whole 60 minutes. It was very fluid which I liked. The session went so fast too! It felt like was over in only a few minutes. It seems a bit difficult for a beginner, but I have done karate for quite a while, so I'm still a bit flexible lol.

I'll be following along to this dvd for a while! - An excellent addition to a healthy life style. I felt extremely good after the first session.

But one problem...

I'm going to have to get my doctors advice on doing yoga because since 2005, when many of my problems started, something happened to my back. I'm not sure if it was in a concert when I got crushed or when If I over-done weight lifthing or just bad posture. My upper back on the left side always goes numb and tingles when I lift something with my left arm, It could be as something as light as a cup.
Back in December 05 I could barely sit up straight without severe back pain, I HAD to have back support. This could be a pinched nerve or something? This is just another on going problem that have not resolved, and I aint told my doctor about it yet. Maybe this could also be a cause for inflammation causing higher CRP. I think its about time that my problems get investigated better. I always leave things because I think they will get better on there own... This is why I get anxious, I'm alright now... actually I'm feeling better than I have in a long time. But if things continue to not get better like my back, my sinus trouble, then no doubt my anxiety will return. At least my palpitations and frequent urination are gone away (signs of anxiety getting better!)

but maybe yoga could fix my back problem... When I did yoga for the 60 minute it felt good and caused no back pain at all. (if anyone ever gets to read any of these messages now or in the future, then please do comment on here if you want).

[Matthewlake]

The omega 3 effect and more yoga

It's been a while now since I started to take high dose omega 3 again, at first the effects were subtle, but now it seems to still be having quite a positive effect on helping me remain calm. But once again I've also noticed an ability to remember/recall things much easier. This seemed to have faded from december onwards, when I stopped taking high dose omega 3, and anxiety increased until it becamse apparent that it was wrecking my health. So I will not make the same mistake again in stopping taking this important fatty acid. I'm also getting that motivation I had back again, where I want to learn more and more...

Now onto yoga, I enjoyed another session today, but not as uch as yesterday because I got interrupted about 5 times, I lost concentration each time and actually jumped when somone knocked my bedroom door. I get into this state of being really relaxed when doing yoga... So I think it's going to have to be one of the first things I do in the day, I'll have to get up a bit earier (been getting up at 10am lately) at about 6am. For anyone that are thinking about CR, or is already doing it, I think yoga is something that you should give a try. When I get a job I think I may even join a yoga class. Things are looking a bit brighter now, and I'm feeling good.

[Matthewlake]

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[Matthewlake]

Being prepared

Summer is nearly over, and it won't be too long before everyone gets their annual flu or cold. Right now I feel susceptible especially with the sinus trouble I've been having. So this has to be sorted very shortly because I hate getting the flu or colds... (as does everyone!). I haven't actually had any since I started CR, even though most of my family were sick around me I somehow got through! - maybe not this time?

Ten days and I see my doctor so hopefully something can be sorted out. I am hesitant to take antibiotics because they hurt my stomach really bad and kills all those nice friendly flora. So I will want to be sure that it is an infection first, because if it is then its incredibly mild (but chronic). I don't get any of the symptoms except discolored thick mucus and nose is mildly inflammed.

Why I don't think its an allergy is because
1. I never had all year round allergy in my life
2. CR has basically totally elminated all symptoms of hay fever
3. Why would another allergy pop up whern my other allergy has basically disappeared due to CR. It makes no sense...

[Matthewlake]

Have some Vitamin C with that green tea?

Am I really getting passed anxiety, or were the supplements that I am taking reducing the effects significantly so that I hardly notice them? After thinking about this I stopped taking high doses of Vitamin C for about 3 days and what I found was an increase in the symptoms associated with anxiety... those adrenaline rushes came back more frequently again, I started to get irritable last night and this morning (can't keep my hands or feet still). So it seems that Vitamin C is VERY effective for me, and maybe you too if you are experiencing any symptoms associated with stress or anxiety.

As I love to drink green tea throughout the day, and have yet to pick up some decaf green tea... I was avoiding too many cups during the day because of the caffeine increasing Cortisol and adrenaline. But now before I start consuming jasmine green tea, I take 1000mg of Vitamin C and don't notice an increase in anxiety related symptoms

(1) Vitamin C supplementation attenuates the increases in circulating cortisol, adrenaline and anti-inflammatory polypeptides following ultramarathon running.
PMID:11590482

(2) Vitamin C: Stress buster
The vitamin helps reduce the effects of stress. It's already everybody's favorite nutritional supplement, linked, however controversially, to preventing the common cold and fighting cancer. But vitamin C recently added a new notch on its belt. The vitamin helps reduce both the physical and psychological effects of stress on people.
http://www.psychologytoday.com/articles/pto-20030425-000001.html

[Matthewlake]

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[Matthewlake]

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[Matthewlake]

Removed by matt

[Matthewlake]

Weight and living longer

I've already posted about this over at the CR society lists. Most of them are fixated on BMI and mortality, and thinks it actually has some importance on the effect of CR on life span. It has crossed my mind a few times about the complications of being really thin, but why are people using studies based on BMI and mortality based on average joes when the CR is not about weight, and also CRers have vastly superior diets to what I would imagine the large majority of people included in these correlation studies are on. It's quite annoying to see it being brought up over and over again because CR isn't just about obesity avoidance, translating BMI - Mortality studies to a bunch of CRONies is silly (IMO). We know that when animals are put on CR they maintain a VERY LEAN body mass, its not suprising that this effect will be included within CR on humans, and why would it be harmful to health? BMI is not the factor in why CR extends maximum lifespan.

- Being thin does not at all mean that you are under some calorie restricted diet, If it did then I would have just continued with my old eating habits which was full of junk food and maintain a nice lean body mass of 18.5.

- Just because one is thin does not mean they are eating an optimal diet that would ensure there is no long standing nutritional deficiencies. It seems people are forgetting just how important maintaining an excellent diet is in getting CR to work..

Do human CR studies count for nothing?

Even when we get remarkable results back from human studies shown that CRers are at the lowest risk of most common killer diseases, they still go on about mortality and BMI, and whats most annoying about it is the fact that they are showing BMI and mortality correlations from a bunch of people that are not even on CR, or are very likely on a CR inadequate diet.

Now granted there are problems with some of fontanna's studies, such as the comparison between slightly overweight people and CRers that have an average BMI of about 19. But still, even without a control the numbers CRers get are very impressive by itself.


What have the studies on humans shown so far?

Well first of all they certainly show that CRers are at LOWER risk of death than the average person (CRers with an average BMI of 19).

CRers hearts function much like younger individuals
CRers have less oxidative and DNA damage
CRers have less risk of stroke
CRers have less inflammation and less risk of cancer
CRers have protection from diabetes
CRers seem to have increased protection from AD and PD
CRers claim to get less infections than prior to CR

And not just that...

CRers have two biomarkers of longevity
Low insulin / high insulin sensitivity
Low Core Body Temperature

what do they want! blood!?!?!! lol

Forget about BMI and mortality, focus on yourselves and take a good look at what recent studies are showing on CRers health and mortality risks from each major killer. CRers are exceptional cases and it is pointless trying to translate the average persons mortality risk to ours, even if they have the same low weights as us. CR is nothing to do with weight, the mechanisms by which CR protects us from certain age related diseases are due to the low calorie intake and not the low BMI.

Calorie Restriction will have minimal impact on lifespan in humans?

all this speculation about CR not working on humans is just speculation, and not evidence against CR working in humans!.

ahhrhhhhhhhhhhh

[Matthewlake]

Removed by matt