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The paper below appears to suggest what may occur with our
nutrients that are detected in our blood.

Stowe HD, Lawler DF, Kealy RD.
Antioxidant status of pair-fed labrador retrievers is
affected by diet
restriction and aging.
J Nutr. 2006 Jul;136(7):1844-8.

PMID: 16772447 http://tinyurl.com/s8nr7

Twenty-four sibling pairs of 8-wk-old Labrador
Retrievers were assigned to an experiment to determine the
effects of diet restriction (75% of control-fed pair mate)
on the quality and span of canine life and to identify
biological markers of aging in dogs. The antioxidant status
of these dogs was monitored by annual assays for serum
retinol (RT), retinyl palmitate (RP), total vitamin A (VA),
vitamin E (VE), selenium (Se), copper (Cu), and
ceruloplasmin (Cp), plasma ascorbic acid (AA), uric acid
(UA), and total peroxyl-radical trapping activity (TRAP),
and whole-blood glutathione peroxidase (Gpx). Data in this
report are for the 6-y period of the experiment when the
dogs were between 5 and 10 y of age. Diet restriction
reduced RT, VE, Cu, and Cp. Aging was associated with
decreased RP, VA, VE, Se, and Cu and with increased RT, Cp,
and Gpx. Female dogs had lower RP, VA, Cu, and Cp than male
dogs. Litter effects were observed for VE, Cu, UA, and Gpx.
Treatment effects on serum RT and Cu suggest that these
variables are not as regulated homeostatically by hepatic
storage as in most other species. Although the antioxidant
profiles did not elucidate how diet restriction contributes
to longevity, they have the potential to enhance our
understanding of canine clinical nutrition and to have
practical applications in formulating canine diets.