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Signal transduction 101: The nexus of signals that age you

 
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PostPosted: Tue Feb 07, 2006 3:54 pm    Post subject: Signal transduction 101: The nexus of signals that age you Reply with quote

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"These networks are central to our understanding of a variety of physiological and pathological conditions, including cancer, diabetes, and longevity." - Genes and Development

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There is a fascinating new paper in the journal Genes and Development that details the current understanding regarding p53, IGF-1, and Akt. All of the proteins have been manipulated in the laboratory to produce increases in the lifespan, and caloric restriction is thought to in part touch upon them.

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