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[A1CR]

> CRBASICS wrote:
>> CRBASICS wrote:
>> In reply, MR wrote:

>> I was at a healthy weight of 110 in late teens. A reduction
>> of even 10% below that would put me at less than 100 Lbs.
>> This is crazy. Did not Dr. Walford recommend getting down to
>> a weight approx equal to that of your late teens or early 20s,
>> and NOT below it?
>
> I'd have to dig out my copies of his books

I dug it out, from my one and only book on CR.

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Weindruch R, Walford RL

The Retardation of Aging and Disease by Dietary Restriction

Charles C Thomas, Springfield (IL), 1988

Chapter 6

Section F

Subsection 3. "How Much Weight Loss, pages 318-9.

One would presume, therefore, that in humans a total
[body weight (BW)]
loss of about 10-25% below the personal set point would be a
reasonable goal
in terms of a positive effect on aging without being too
excessive to
threaten health. While depending on the actual starting
weight of the
individual, i.e., thin to average to obese, a 25 percentage
BW loss
approaches, but does not enter a fullblown anorexia status,
which of course
should be avoided.

The set point for individuals whose BW has been stable
since ages 20-30
is precisely that BW. For those who have gradually gained
BW with age, the
appropriate set point in terms of a DR regimen is uncertain.
In rats the
capacity for thermogenesis is lost by 6.5 months of age
(Rothwell & Stock,
1983). A similar phenomenon might in part underlie the human
tendency to
gain BW with age. For such as these, we suggest the target
"set point"
would be their weight at 20-30 years of age.


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