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[A1CR]

How does intermittent fasting with or without food that
leads to not eating
as much as we might eat otherwise affect disease risk
factors? Better
things happen when the intermittent fasting is combined with
eating-restricting foods, it seems. Etc? Okay. The below
paper is not
pdf-availed and in Chinese for the text, it seems.

Shen XD, Hua WG, Chu WZ, Xu F, Wang YY, Chen HJ.
[Physiological and biochemical effects of intermittent
fasting combined with
hunger-resistant food on mice.]
Zhong Xi Yi Jie He Xue Bao. 2006 Nov;4(6):589-592. Chinese.
PMID: 17090373

Objective: To observe the physiological and biochemical
effects of
intermittent fasting combined with hunger-resistant food on
mice, and to
evaluate the safety and beneficial effects of this regimen.

Methods: One hundred and forty-four adult ICR mice were
divided into 4
groups: standard feed AL group (ad libitum intake of
standard feed),
hunger-resistant food AL group (ad libitum intake of
hunger-resistant food),
standard feed IF group (feeding standard feed and fasting on
alternate
days), and hunger-resistant food IF group (feeding
hunger-resistant food and
fasting on alternate days). The experiment lasted for 4-8
weeks and all mice
drank water freely. The quality of life, body weight,
fasting blood glucose,
serum lipid, blood routine test, liver and kidney functions
as well as the
viscera indexes were examined.

Results: Compared to the standard feed AL group, the caloric
taking and the
increment of body-weight were reduced (P<0.01), and the
viscera indexes of
the liver and kidney were elevated (P<0.05) in the
hunger-resistant food AL
group and the hunger-resistant food IF group, the values of
fasting blood
glucose were reduced in standard feed IF group and
hunger-resistant food IF
group (P<0.01), the value of triglycerides was reduced in
hunger-resistant
food IF group (P<0.05), while the quality of life, blood
routine test as
well as the liver and kidney functions were not obviously
affected in the
hunger-resistant food AL group, standard feed IF group and
hunger-resistant
food IF group.

Conclusion: The regimen of intermittent fasting combined with
hunger-resistant food is safe and beneficial to metabolic
regulation, such
as controlling body-weight and adjusting blood glucose and
serum lipid. It
is expected that development of this regimen will be helpful
to the control
of obesity and diabetes, etc.