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CRONie A wrote

>>CRONie B wrote:

>>> I enjoyed seeing the alpha-lipoic acid and
>>> other supplements gave no detectable benefits.

> I am really shocked! You seem to be saying that you "enjoyed" seeing that
> alpha-lipoic acid and other supplements gave no detectable benefits.

I am a skeptic for expensive, not-part-of-foods supplements
and chemicals,
their vendors, their developers and their advocates.

> What I read in the transcript is:
>
> (Walford): " Anti-oxidant dietary supplements are no substitute for
> calorie
> restriction. They don't seem to affect life-span one way or the other."
>
> Since Dr. Walford made this statement (and perhaps a specific one on alpha
> -lipoic acid, which I may have missed in the text version) over six years
> have passed. I took the time to check PubMed on "alpha-lipoic acid"; it
> shows a total of 2139 citations, of which there are 680 papers on ALA
> published since January 2001, many of which seem to show that the use of
> ALA
> may be quite beneficial. (This is certainly true for many other
> supplements,
> phytochemicals in particular.)

As I recall, it was Dr. Weindruch who made the statements
while showing the
obviously more active and healthy appearing CRed that
contrasted sharply
with the animals supplemented with all the supplements
thought and advocated
at the time to promote health and even extend lives.
Resveratrol and many
more such products have made their way into the literature
since 2000, but
much was done prior the previous six years.

> You really dare to discard all the research done during six years and
> "enjoy" old statements that don't stand up to today's knowledge base, and
> instead feed on today's prejudices and ignorance???

People "knew" for decades in well-documented literature that
herpes simplex
virus caused cervical cancer, until a completely different
virus was found
to be the sole infectious agent known to cause cervical
cancer. I state
this only because this is an example of which I am
intimately aware.

> Of course, I don't restrict "dietary supplements" to the kind of
> "anti-oxidants" prevalent during the Nineties such as Vitamins A, Bs, C,
> E,
> beta-carotene etc., I include the whole big bag of phytochemicals that do
> wonders on a molecular, cellular and cell-nuclear level far beyond mere
> anti-oxidant activity......
> If you and others in this group still think that those "supplements give
> no
> detectable benefits", you are omitting an essential part of advanced CR
> and
> CRON and - as I begin to see it from my own very positive and encouraging
> experience - CRONOS (-OS standing for optimal supplementation) - which is
> a
> beautiful and very meaningful word in itself that may symbolize our
> involvement in health and death . . .

Is it clearly documented that obtaining greater than 100% of
the RDAs of
vitamins and minerals can benefit a significant percentage
of the
population?